Chemical exposure in manufacture of phenoxy herbicides and chlorophenols and in spraying of phenoxy herbicides
Identifieur interne : 00D916 ( Main/Exploration ); précédent : 00D915; suivant : 00D917Chemical exposure in manufacture of phenoxy herbicides and chlorophenols and in spraying of phenoxy herbicides
Auteurs : Timo Kauppinen [Finlande] ; Manolis Kogevinas [France] ; Eric Johnson [États-Unis] ; Heiko Becher [Allemagne] ; Pier-Alberto Bertazzi [Italie] ; H. Bas Bueno De Mesquita [Pays-Bas] ; David Coggon [Royaume-Uni] ; Lois Green [Canada] ; Margareta Littorin [Suède] ; Elsebeth Lynge [Danemark] ; John Mathews [Australie] ; Manfred Neuberger [Autriche] ; John Osman [Royaume-Uni] ; Brian Pannett [Royaume-Uni] ; Neil Pearce [Nouvelle-Zélande] ; Regina Winkelmann [France] ; Rodolfo Saracci [France]Source :
- American Journal of Industrial Medicine [ 0271-3586 ] ; 1993-06.
Descripteurs français
- Wicri :
- topic : Acide, Herbicide, Pesticide, équipement de protection.
English descriptors
- KwdEn :
- Acid, Additive, Alkali, Amine, Biological monitoring, Boom spraying, Cancer mortality, Cancer risks, Carbon tetrachloride, Chemical agents, Chlorophenol, Chlorophenols, Chlorophenoxy, Chlorophenoxy herbicides, Cohort, Derivative, Dermal absorption, Dioxin, Emulsifier, Exposure data, German plant, Herbicide, Herbicide sprayers, Iarc, Iarc study, Industrial hygiene data, Isomer, Kauppinen, Latest year, Manufacturing plants, Mcpa, Mcpa mcpp, Mcpb, Mcpp, Median, Median concentration, Occupational exposure, Other chemicals, Other chlorophenols, Other pesticides, Packer, Pcoc, Pesticide, Phenol, Phenoxy, Phenoxy acids, Phenoxy herbicide manufacturing plants, Phenoxy herbicides, Production figures, Production workers, Protective equipment, Serum levels, Serum tcdd levels, Sprayer, Sprayer cohorts, Synthesis formulation, Synthesis formulation germany, Synthesis workers, Tcdd, Tcdd levels, Tecb, Urine, Wood preservation, Work environment, Zealand.
- Teeft :
- Acid, Additive, Alkali, Amine, Biological monitoring, Boom spraying, Cancer mortality, Cancer risks, Carbon tetrachloride, Chemical agents, Chlorophenol, Chlorophenols, Chlorophenoxy, Chlorophenoxy herbicides, Cohort, Derivative, Dermal absorption, Dioxin, Emulsifier, Exposure data, German plant, Herbicide, Herbicide sprayers, Iarc, Iarc study, Industrial hygiene data, Isomer, Kauppinen, Latest year, Manufacturing plants, Mcpa, Mcpa mcpp, Mcpb, Mcpp, Median, Median concentration, Occupational exposure, Other chemicals, Other chlorophenols, Other pesticides, Packer, Pcoc, Pesticide, Phenol, Phenoxy, Phenoxy acids, Phenoxy herbicide manufacturing plants, Phenoxy herbicides, Production figures, Production workers, Protective equipment, Serum levels, Serum tcdd levels, Sprayer, Sprayer cohorts, Synthesis formulation, Synthesis formulation germany, Synthesis workers, Tcdd, Tcdd levels, Tecb, Urine, Wood preservation, Work environment, Zealand.
Abstract
Exposure patterns are reported for manufacturing and sprayer cohorts incorporated in the “IARC International Register of Workers exposed to Phenoxy Herbicides and Contaminants.” Information was based on company questionnaires, company reports, plant visits, and serum 2,3,7,8‐TCDD measurements. In addition to phenoxy herbicides and chlorophenols, workers in manufacturing plants may have been exposed to raw materials, process chemicals, other agents synthesized or formulated, and impurities of all these agents. Sprayers also had a complex exposure pattern, including phenoxy herbicides and some other pesticides, their carriers and additives, and residues of chemicals formed during manufacture. Occurrence of agents, including dioxins, varied between countries. Biological monitoring and industrial hygiene data were rarely available, most since the late 1970s. Exposure of workers depended mainly on the jobs they performed, but several factors influenced level of exposure. A quantitative exposure classification is not feasible in this study. Semiquantitative exposure estimates may be derived through a critical interpretation of biological monitoring and industrial hygiene data together with individual work histories. © 1993 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/ajim.4700230607
Affiliations:
- Allemagne, Australie, Autriche, Canada, Danemark, Finlande, France, Italie, Nouvelle-Zélande, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Auvergne-Rhône-Alpes, Bade-Wurtemberg, District de Karlsruhe, Hollande-Septentrionale, Hovedstaden, Lombardie, Ohio, Rhône-Alpes, Vienne (Autriche)
- Amsterdam, Copenhague, Heidelberg, Lyon, Milan, Vienne (Autriche)
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001F02
- to stream Istex, to step Curation: 001F02
- to stream Istex, to step Checkpoint: 002A31
- to stream Main, to step Merge: 00EB37
- to stream Main, to step Curation: 00D916
Le document en format XML
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Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Correspondence address: Institute of Occupational Health, Department of Epidemiology and Biostatistics, Topeliuksenk, 41aA, SF‐00250 Helsinki</wicri:regionArea><wicri:noRegion>SF‐00250 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Johnson, Eric" sort="Johnson, Eric" uniqKey="Johnson E" first="Eric" last="Johnson">Eric Johnson</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>National Institute of Environmental Health Sciences (NIEHS), Cincinnati</wicri:cityArea></affiliation></author><author><name sortKey="Becher, Heiko" sort="Becher, Heiko" uniqKey="Becher H" first="Heiko" last="Becher">Heiko Becher</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Bertazzi, Pier Lberto" sort="Bertazzi, Pier Lberto" uniqKey="Bertazzi P" first="Pier-Alberto" last="Bertazzi">Pier-Alberto Bertazzi</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>National Institute of Public Health & Environmental Protection, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Coggon, David" sort="Coggon, David" uniqKey="Coggon D" first="David" last="Coggon">David Coggon</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Environmental Epidemiology Unit, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Green, Lois" sort="Green, Lois" uniqKey="Green L" first="Lois" last="Green">Lois Green</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Hydro, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Littorin, Margareta" sort="Littorin, Margareta" uniqKey="Littorin M" first="Margareta" last="Littorin">Margareta Littorin</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Lund University, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Lynge, Elsebeth" sort="Lynge, Elsebeth" uniqKey="Lynge E" first="Elsebeth" last="Lynge">Elsebeth Lynge</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Cancer Registry, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Mathews, John" sort="Mathews, John" uniqKey="Mathews J" first="John" last="Mathews">John Mathews</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Menzies School of Health Research, Casuarina</wicri:regionArea><wicri:noRegion>Casuarina</wicri:noRegion></affiliation></author><author><name sortKey="Neuberger, Manfred" sort="Neuberger, Manfred" uniqKey="Neuberger M" first="Manfred" last="Neuberger">Manfred Neuberger</name><affiliation wicri:level="3"><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Environmental Hygiene, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Osman, John" sort="Osman, John" uniqKey="Osman J" first="John" last="Osman">John Osman</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health and Safety Executive, Bootle</wicri:regionArea><wicri:noRegion>Bootle</wicri:noRegion></affiliation></author><author><name sortKey="Pannett, Brian" sort="Pannett, Brian" uniqKey="Pannett B" first="Brian" last="Pannett">Brian Pannett</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Environmental Epidemiology Unit, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Pearce, Neil" sort="Pearce, Neil" uniqKey="Pearce N" first="Neil" last="Pearce">Neil Pearce</name><affiliation wicri:level="1"><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Wellington School of Medicine, Wellington</wicri:regionArea><wicri:noRegion>Wellington</wicri:noRegion></affiliation></author><author><name sortKey="Winkelmann, Regina" sort="Winkelmann, Regina" uniqKey="Winkelmann R" first="Regina" last="Winkelmann">Regina Winkelmann</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Saracci, Rodolfo" sort="Saracci, Rodolfo" uniqKey="Saracci R" first="Rodolfo" last="Saracci">Rodolfo Saracci</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">American Journal of Industrial Medicine</title><title level="j" type="alt">AMERICAN JOURNAL OF INDUSTRIAL MEDICINE</title><idno type="ISSN">0271-3586</idno><idno type="eISSN">1097-0274</idno><imprint><biblScope unit="vol">23</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="903">903</biblScope><biblScope unit="page" to="920">920</biblScope><biblScope unit="page-count">18</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="1993-06">1993-06</date></imprint><idno type="ISSN">0271-3586</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0271-3586</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acid</term><term>Additive</term><term>Alkali</term><term>Amine</term><term>Biological monitoring</term><term>Boom spraying</term><term>Cancer mortality</term><term>Cancer risks</term><term>Carbon tetrachloride</term><term>Chemical agents</term><term>Chlorophenol</term><term>Chlorophenols</term><term>Chlorophenoxy</term><term>Chlorophenoxy herbicides</term><term>Cohort</term><term>Derivative</term><term>Dermal absorption</term><term>Dioxin</term><term>Emulsifier</term><term>Exposure data</term><term>German plant</term><term>Herbicide</term><term>Herbicide sprayers</term><term>Iarc</term><term>Iarc study</term><term>Industrial hygiene data</term><term>Isomer</term><term>Kauppinen</term><term>Latest year</term><term>Manufacturing plants</term><term>Mcpa</term><term>Mcpa mcpp</term><term>Mcpb</term><term>Mcpp</term><term>Median</term><term>Median concentration</term><term>Occupational exposure</term><term>Other chemicals</term><term>Other chlorophenols</term><term>Other pesticides</term><term>Packer</term><term>Pcoc</term><term>Pesticide</term><term>Phenol</term><term>Phenoxy</term><term>Phenoxy acids</term><term>Phenoxy herbicide manufacturing plants</term><term>Phenoxy herbicides</term><term>Production figures</term><term>Production workers</term><term>Protective equipment</term><term>Serum levels</term><term>Serum tcdd levels</term><term>Sprayer</term><term>Sprayer cohorts</term><term>Synthesis formulation</term><term>Synthesis formulation germany</term><term>Synthesis workers</term><term>Tcdd</term><term>Tcdd levels</term><term>Tecb</term><term>Urine</term><term>Wood preservation</term><term>Work environment</term><term>Zealand</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Acid</term><term>Additive</term><term>Alkali</term><term>Amine</term><term>Biological monitoring</term><term>Boom spraying</term><term>Cancer mortality</term><term>Cancer risks</term><term>Carbon tetrachloride</term><term>Chemical agents</term><term>Chlorophenol</term><term>Chlorophenols</term><term>Chlorophenoxy</term><term>Chlorophenoxy herbicides</term><term>Cohort</term><term>Derivative</term><term>Dermal absorption</term><term>Dioxin</term><term>Emulsifier</term><term>Exposure data</term><term>German plant</term><term>Herbicide</term><term>Herbicide sprayers</term><term>Iarc</term><term>Iarc study</term><term>Industrial hygiene data</term><term>Isomer</term><term>Kauppinen</term><term>Latest year</term><term>Manufacturing plants</term><term>Mcpa</term><term>Mcpa mcpp</term><term>Mcpb</term><term>Mcpp</term><term>Median</term><term>Median concentration</term><term>Occupational exposure</term><term>Other chemicals</term><term>Other chlorophenols</term><term>Other pesticides</term><term>Packer</term><term>Pcoc</term><term>Pesticide</term><term>Phenol</term><term>Phenoxy</term><term>Phenoxy acids</term><term>Phenoxy herbicide manufacturing plants</term><term>Phenoxy herbicides</term><term>Production figures</term><term>Production workers</term><term>Protective equipment</term><term>Serum levels</term><term>Serum tcdd levels</term><term>Sprayer</term><term>Sprayer cohorts</term><term>Synthesis formulation</term><term>Synthesis formulation germany</term><term>Synthesis workers</term><term>Tcdd</term><term>Tcdd levels</term><term>Tecb</term><term>Urine</term><term>Wood preservation</term><term>Work environment</term><term>Zealand</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Acide</term><term>Herbicide</term><term>Pesticide</term><term>équipement de protection</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Exposure patterns are reported for manufacturing and sprayer cohorts incorporated in the “IARC International Register of Workers exposed to Phenoxy Herbicides and Contaminants.” Information was based on company questionnaires, company reports, plant visits, and serum 2,3,7,8‐TCDD measurements. In addition to phenoxy herbicides and chlorophenols, workers in manufacturing plants may have been exposed to raw materials, process chemicals, other agents synthesized or formulated, and impurities of all these agents. Sprayers also had a complex exposure pattern, including phenoxy herbicides and some other pesticides, their carriers and additives, and residues of chemicals formed during manufacture. Occurrence of agents, including dioxins, varied between countries. Biological monitoring and industrial hygiene data were rarely available, most since the late 1970s. Exposure of workers depended mainly on the jobs they performed, but several factors influenced level of exposure. A quantitative exposure classification is not feasible in this study. Semiquantitative exposure estimates may be derived through a critical interpretation of biological monitoring and industrial hygiene data together with individual work histories. © 1993 Wiley‐Liss, Inc.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Canada</li><li>Danemark</li><li>Finlande</li><li>France</li><li>Italie</li><li>Nouvelle-Zélande</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Bade-Wurtemberg</li><li>District de Karlsruhe</li><li>Hollande-Septentrionale</li><li>Hovedstaden</li><li>Lombardie</li><li>Ohio</li><li>Rhône-Alpes</li><li>Vienne (Autriche)</li></region><settlement><li>Amsterdam</li><li>Copenhague</li><li>Heidelberg</li><li>Lyon</li><li>Milan</li><li>Vienne (Autriche)</li></settlement></list><tree><country name="Finlande"><noRegion><name sortKey="Kauppinen, Timo" sort="Kauppinen, Timo" uniqKey="Kauppinen T" first="Timo" last="Kauppinen">Timo Kauppinen</name></noRegion><name sortKey="Kauppinen, Timo" sort="Kauppinen, Timo" uniqKey="Kauppinen T" first="Timo" last="Kauppinen">Timo Kauppinen</name></country><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name></region><name sortKey="Saracci, Rodolfo" sort="Saracci, Rodolfo" uniqKey="Saracci R" first="Rodolfo" last="Saracci">Rodolfo Saracci</name><name sortKey="Winkelmann, Regina" sort="Winkelmann, Regina" uniqKey="Winkelmann R" first="Regina" last="Winkelmann">Regina Winkelmann</name></country><country name="États-Unis"><region name="Ohio"><name sortKey="Johnson, Eric" sort="Johnson, Eric" uniqKey="Johnson E" first="Eric" last="Johnson">Eric Johnson</name></region></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Becher, Heiko" sort="Becher, Heiko" uniqKey="Becher H" first="Heiko" last="Becher">Heiko Becher</name></region></country><country name="Italie"><region name="Lombardie"><name sortKey="Bertazzi, Pier Lberto" sort="Bertazzi, Pier Lberto" uniqKey="Bertazzi P" first="Pier-Alberto" last="Bertazzi">Pier-Alberto Bertazzi</name></region></country><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name></region></country><country name="Royaume-Uni"><noRegion><name sortKey="Coggon, David" sort="Coggon, David" uniqKey="Coggon D" first="David" last="Coggon">David Coggon</name></noRegion><name sortKey="Osman, John" sort="Osman, John" uniqKey="Osman J" first="John" last="Osman">John Osman</name><name sortKey="Pannett, Brian" sort="Pannett, Brian" uniqKey="Pannett B" first="Brian" last="Pannett">Brian Pannett</name></country><country name="Canada"><noRegion><name sortKey="Green, Lois" sort="Green, Lois" uniqKey="Green L" first="Lois" last="Green">Lois Green</name></noRegion></country><country name="Suède"><noRegion><name sortKey="Littorin, Margareta" sort="Littorin, Margareta" uniqKey="Littorin M" first="Margareta" last="Littorin">Margareta Littorin</name></noRegion></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Lynge, Elsebeth" sort="Lynge, Elsebeth" uniqKey="Lynge E" first="Elsebeth" last="Lynge">Elsebeth Lynge</name></region></country><country name="Australie"><noRegion><name sortKey="Mathews, John" sort="Mathews, John" uniqKey="Mathews J" first="John" last="Mathews">John Mathews</name></noRegion></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Neuberger, Manfred" sort="Neuberger, Manfred" uniqKey="Neuberger M" first="Manfred" last="Neuberger">Manfred Neuberger</name></region></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Pearce, Neil" sort="Pearce, Neil" uniqKey="Pearce N" first="Neil" last="Pearce">Neil Pearce</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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